Boisseau Nathalie - Autre

Je suis actuellement professeur à l’UFRSTAPS, l’université Blaise Pascal et Clermont-Ferrand, et directrice du laboratoire AME2P.

De 2000 à 2010, j’ai travaillé en tant que Maître de Conférences, Université de Poitiers, Faculté des Sciences du Sport.

  • 1999 : Doctorat STAPS, Université de Rennes II
  • 1995 : DEA « Adaptation, Développement, Sport et Santé » à la Faculté de Médecine de Montpellier.
  • 1994 : Maîtrise STAPS, Université de Rennes II.

Mon domaine d’excellence est la physiologie du sport :

  • Exercice
  • Métabolisme énergétique
  • Composition corporelle, hormones et nutrition.
Publications :

Quick benefits of interval-training versus continuous training: a Dual energy X-ray Absorptiometry comparative study.

To examine the preparation phase for the snatch lift in Olympic weight lifting. Two behavioral periods were studied, each corresponding to specific mental processes: a stance in front of the bar and placement of hands on the bar. Each period was hypothesized to elicit different responses of autonomic-nervous-system activity.

Demande d'informations ?

Nutritional and exercise interventions variably affect estrogen receptor expression in the adipose tissue of male rats.

Observing somebody performing an action has been shown to elicit neuronal activity in the premotor cortex. This paper investigated physiological effect of observing an effortful action at the peripheral level. As Autonomic Nervous System responses reflect central nervous system processes such as movement planning and programming, it was expected that observing an action would elicit a pattern of ANS responses matching those recorded during actual movement. 12 male subjects, ages 23 to 28 years (M = 25.5, SD = 1.9), were selected as they were experienced in weight lifting.

Demande d'informations ?

Neuregulin 1 improves glucose tolerance in adult and old rats. Diabetes & Metabolism.

Studies both in vitro and ex vivo of rodent skeletal muscle have highlighted the potential involvement of neuregulin 1 (NRG1) in glucosemetabolism regulation, yet nothing is known of the role of NRG1 in systemic glucose homoeostasis. For this reason, it was hypothesized that systemic delivery of NRG1 might improve glucose tolerance and that the effect might be age-dependent.

Demande d'informations ?

Exercise training and return to a well-balanced diet activate the neuregulin 1 / ErbB pathway in skeletal muscle of obese rats.

Some studies suggest that neuregulin 1 (NRG1) could be involved in the regulation of skeletal muscle energy metabolism in rodents. Here we assessed whether unbalanced diet is associated with alterations of the NRG1 signalling pathway and whether exercise and diet might restore NRG1 signalling in skeletal muscle of obese rats. We show that diet-induced obesity does not impair NRG1 signalling in rat skeletal muscle. We also report that endurance training and a well-balanced diet activate the NRG1 signalling in skeletal muscle of obese rats, possibly via a new mechanism mediated by the protease ADAM17. These results suggest that some beneficial effects of physical activity and diet in obese rats could be partly explained by stimulation of the NRG1 signalling pathway.

Demande d'informations ?

Beneficial effects of an intradialytic cycling exercise program in ESKD patients. Applied Physiology, Nutrition, and Metabolism

Auteurs : Groussard C, Rouchon-Isnard M, Coutard C, Romain F, Malarde L, Lemoine-Morel S, Martin B, Pereira B,  BOISSEAU N.

Demande d'informations ?

Maximal fat oxidation but not aerobic capacity is affected by oral contraceptive use in young healthy women.

Auteurs : Isacco L, Thivel D, Pereira B, Duclos M, BOISSEAU N. – European Journal of Applied Physiology, 115(5):937-45, 2015

Demande d'informations ?

Neuregulin 1 improves glucose tolerance in db/db mice.

In vitro experiments using rodent skeletal muscle cells suggest that neuregulin 1 (NRG1) is involved in glucose metabolism regulation, although no study has evaluated the role of NRG1 in systemic glucose homeostasis. The purpose of this study was to investigate the effect of chronic and acute NRG1 treatment on glucose homeostasis in db/db mice.

Demande d'informations ?

Effects of adipose tissue distribution on maximal lipid oxidation rate during exercise in normal weight women.

Fat mass localization affects lipid metabolism differently at rest and during exercise in overweight and normal-weight subjects. The aim of this study was to investigate the impact of a low vs high ratio of abdominal to lower-body fat mass (index of adipose tissue distribution) on the exercise intensity (Lipox(max)) that elicits the maximum lipid oxidation rate in normal-weight women.

Demande d'informations ?

Comparison of oxygen consumption in rats during uphill (concentric) and downhill (eccentric) treadmill exercise tests.

The study of the physiological adaptations of skeletal muscle in response to eccentric (ECC) contraction is based on protocols in which exerciseintensities are determined relative to the concentric (CON) reference exercise (as percentage of the CON maximal oxygen consumption, or VO2max). In order to use similar exercise protocols in rats, we compared the VO2 values during uphill (CON) and downhill (ECC) running tests.

Demande d'informations ?

Exercise per se masks oral contraceptive-induced postprandial lipid mobilization.

Because of their hormonal content, oral contraceptives may alter lipolytic activity under resting or exercise conditions in women. The aim of the present study was to compare lipid mobilization in a postprandial state at rest and during exercise in oral contraceptive users (OC+) versus nonusers (OC-). The metabolic (glucose, glycerol, free fatty acids) and hormonal (insulin, atrial natriuretic peptide (ANP), growth hormone, insulin-like growth factor-1 (IGF-1), and catecholamines) concentrations were determined in 11 OC+ (monophasic low-dose oral contraceptives) and 10 OC- during a resting and an exercise session (45 min at 65% maximal oxygen consumption).

Demande d'informations ?

Fat Mass Localization Alters Fuel Oxidation during Exercise in Normal Weight Women.

Abdominal and lower body fat mass tissues exhibit particular metabolic profiles at rest and during exercise. However, data are missing in normal weight women during exercise. The purpose of this study was to investigate the effect of low (LA/LB) and high (HA/LB) abdominal to lower body (A/LB) fat mass ratio on metabolic and hormonal responses during exercise in premenopausal normal weight women.

Demande d'informations ?

Oral contraception but not menstrual cycle phase is associated with increased free cortisol levels and low HPA axis reactivity.

In females, estrogen is a potential modulator of cortisol response to stressors. The aim of this study was to determine the influence of menstrual cycle phase, oral contraception (OC) use and exercise training on hypothalamo-pituitary-adrenal (HPA) axis activity and reactivity after physical stress.

Demande d'informations ?

Regular exercise limits alcohol effects on trabecular, cortical thickness and porosity,and osteocyte apoptosis in the rat.

Excessive alcohol consumption is known to be a cause of secondary osteoporosis whereas physical activity is recommended in prevention of osteoporosis. This study was designed to analyze the effects of physical exercise on bone parameters in chronic alcohol-fed rats.

Demande d'informations ?

Repeatability and relative validity of a quantitative food-frequency questionnaire among French adults.

A 50-item self-administered food frequency questionnaire (FFQ) was developed for French adults, to assess the intake of energy, 10 macronutrients, 11 vitamins, and 11 minerals, and to be used in the context of a medical consultation.

Demande d'informations ?

Knee extension strength in obese and non-obese male adolescents.

Auteurs : Abdelmoula A, Martin V, Bouchant A, Walrand S, Lavet C, Taillardat M, Maffiuletti NA, BOISSEAU N, Duché P, Ratel S. – Applied Physiology, Nutrition and Metabolism, 37(2):269-75.

Demande d'informations ?

Alcohol and bone: Review of dose effects and mechanisms.

Auteurs : Maurel DB, BOISSEAU N, Benhamou CL, Jaffré C. – Osteoporosis International. 23 (1): 1-16.

Demande d'informations ?

Circulating androgens in women: exercise-induced changes revisited

Auteurs : Enea C, BOISSEAU N, Fargeas-Gluck MA, Diaz V, Dugué B. – Sports Medicine. 41 (1), 1-15, 2011.

Demande d'informations ?